London’s Spex Capital, a number one early-stage investor tackling international healthcare challenges by way of HealthTech options, right this moment introduced the primary €30 million dedication to its flagship €100 million Enterprise HealthTech Fund.
The fund will make investments globally in early-stage HealthTech startups, from Seed to Collection A/B, with investments of as much as €5 million.
Spex has partnered with EIT Digital and Penn Drugs/LGH, a number one mutli-hospital well being system within the US that handles over 7 million sufferers every year.
Claudio D’Angelo, Founder and CEO of Spex Capital, stated: “Healthcare faces immense challenges worldwide with ageing populations creating rising affected person demand and systemic value pressures. Our true power isn’t just the amount of corporations we see, however the unparalleled energy of our distribution community to offer them with important business and medical validation.”
A number of different funds have additionally entered or expanded throughout the European healthtech funding area in 2025, indicating sustained investor urge for food for early-stage digital well being and medical innovation.
London-based Meridian Health Ventures launched a €44.7 million transatlantic fund to again HealthTech startups scaling between the UK and the US. Belgium’s Capricorn Partners introduced a €51 million first shut for its Well being-Tech Fund II, focusing on diagnostics, digital well being, and life-science ventures. In France, M2care secured €26 million to speed up enterprise studio exercise in healthcare innovation.
Towards this backdrop, Spex Capital’s €100 million Enterprise HealthTech Fund sits among the many largest of the present European initiatives centered on early-stage well being expertise, highlighting rising institutional confidence within the sector’s potential.
Its partnerships with EIT Digital, Penn Drugs, and long-standing hyperlinks to the NHS present entry to intensive validation networks, an element typically cited as a bottleneck in scaling well being applied sciences.
In a 12 months the place European healthtech funding surpassed €4 billion in early 2025, in line with EU-Startups’ sector overview, Spex Capital’s entry alerts sustained investor confidence in digital well being and medical innovation.
“The provision is robust, however the validation we ship by way of our community is the game-changer. Digital HealthTech is vital to addressing these challenges, and with this fund, our new partnerships, and a world-class advisory community, we’re uniquely positioned to assist visionary founders delivering transformative options worldwide,” added D’Angelo.
Based in 2021 by serial entrepreneur Claudio D’Angelo, Spex Capital focuses on commercialising and scaling digital well being and medical expertise options throughout main healthcare supply techniques worldwide.
The corporate additionally introduced the appointment of Lord Markham, former UK Well being Minister, as Chair of the Board. He has intensive expertise throughout the general public, non-public and voluntary sectors, notably within the enterprise area the place he co-founded a HealthTech enterprise, Cignpost, which grew from €0 to €350 million turnover in 1 12 months.
Lord Markham, Chairman, stated: ”I’m delighted to hitch Spex Capital at such a pivotal second for HealthTech. This scale-up fund will unleash groundbreaking startups. I look ahead to working with Claudio and the staff as we speed up the event and adoption of applied sciences that enhance affected person outcomes and reshape healthcare supply globally. “
EU-Startups beforehand lined the agency in February 2023, when Spex Capital first introduced plans for its €100 million HealthTech fund.
