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    Home»Startups»Addressing Europe’s obesity burden, French MedTech startup Annette closes €2 million round for structured GLP-1 support
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    Addressing Europe’s obesity burden, French MedTech startup Annette closes €2 million round for structured GLP-1 support

    Editor Times FeaturedBy Editor Times FeaturedDecember 4, 2025No Comments5 Mins Read
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    Annette, a Paris-based medical help platform devoted to continual weight problems care and sufferers utilizing GLP-1 remedies, has raised €2 million to supply a follow-up delivered by a medical workforce and coordinated by means of a medical companion app.

    The spherical was led by Redstone, Ring Capital and AFI Ventures (Ventech – early stage fund) Clover VC, and Gfund.

    “We use each medical and subjective knowledge (satiety, vitality, signs…) to synchronise the care workforce round every affected person, detect early alerts, and alter on the proper second. Know-how acts as a security web: it augments the human contact – it by no means replaces it,” says Gwen Le Calvez, co-founder and Chief Product and Know-how Officer, Annette.

    Annette’s €2 million elevate comes amid a gentle stream of 2025 European funding into digital chronic-care and obesity-related HealthTech.

    In Poland, Holi secured €3 million to broaden its data-driven digital weight problems clinic throughout Europe, whereas Doctor.One raised €4 million to scale its asynchronous chronic-care mannequin, which incorporates help for metabolic and obesity-related circumstances. In France – Annette’s house market – RDS raised €14 million to industrialise its remote-monitoring patch, signalling ongoing investor confidence in French HealthTech infrastructure extra broadly.

    Collectively, these 2025 rounds quantity to roughly €21 million of capital flows in adjoining chronic-care and monitoring options, rising to ~€23 million when together with Annette.

    Inside this context, Annette stands out as one of many few French corporations particularly concentrating on GLP-1–supported weight problems care, and its elevate aligns with the broader 2025 pattern in the direction of built-in, multidisciplinary chronic-care platforms throughout Europe.

    “These outcomes are usually not pushed by the remedy alone: they happen when medicine is paired with construction, dietary steerage, emotional help, and a gradual adaptation to the physique’s rhythm. That is exactly what Annette delivers – turning a remedy into a real long-term care pathway,” provides François-Xavier Trancart, co-founder and CEO, Annette.

    Based in 2024 by two repeat entrepreneurs – François-Xavier Trancart (Artsper) and Gwen Le Calvez (Birdie) – Annette buildings long-term GLP-1 and continual weight problems care by means of a multidisciplinary workforce coordinated through a companion-app, making certain remedy security and serving to sufferers obtain lasting outcomes.

    Annette supplies a companion-app designed as a pure extension of medical take care of sufferers beginning GLP-1 remedies. The platform organizes GLP-1 follow-up round a multidisciplinary medical workforce:

    • A personal messaging channel with Annette specialists (dietitians, bodily exercise coaches, psychologists, and so on.)
    • Guided pathways tailor-made to every section of the remedy
    • Monitoring of key bodily alerts: starvation, satiety, vitality, digestion, remedy adherence
    • Steerage towards a doctor for analysis, dose changes, or stabilisation
    • A supportive group, so sufferers by no means progress alone

    Immediately, greater than 1,000 sufferers are supported by means of Annette, which reportedly boasts an average weight loss above clinical trial outcomes, a 90% retention fee at three months, and an NPS of +70.

    Annette’s currentcare mannequin is predicated on a €49 month-to-month subscription.

    “At AFI Ventures, we again entrepreneurs who use know-how to deal with society’s most urgent challenges. Weight problems is clearly one in every of them. What makes us significantly keen about Annette is the uncommon mixture of an formidable imaginative and prescient, scientific rigor, and a product able to creating significant impression for tens of millions of individuals. We’re satisfied that the Annette workforce is constructing an answer that may actually transfer the needle,” says Constantin de Chaudenay, Investor at AFI Ventures

    Weight problems is a continual and multifactorial illness, influenced by biology, feelings, and atmosphere. It’s now recognided as a significant public well being problem in France and throughout Europe. Based on the 2024 nationwide OFÉO examine:

    • 48.8% of adults in France are obese or dwelling with weight problems
    • together with 18% with weight problems – that’s almost 10 million folks

    Annette explains that if care pathways don’t enhance, the prevalence of weight problems might attain 30% of the inhabitants by 2030.

    The arrival of GLP-1 remedies (Wegovy, Mounjaro) marks a significant milestone, however the firm outlines that worldwide expertise has proven the dangers when these medicines are used with out correct supervision: remoted prescriptions, lack of follow-up, and important weight regain.

    With out dietary construction, emotional help, tailor-made bodily exercise, and ongoing medical follow-up, the advantages fade and the chance of regain will increase. That is exactly the place Annette seems to be to return in.

    “The remedy can cut back urge for food. However it doesn’t rewrite consuming habits or the connection with one’s physique. Medical and behavioral help makes it attainable to remodel how one eats, strikes, and feels. It’s the mixture of each that actually shifts the load trajectory – and makes it final,” explains Dr Lysiane Jubin, Chief Medical Officer, Annette.

    This new funding spherical will allow Annette to scale its mannequin to tens of 1000’s of sufferers, in France after which throughout Europe, specializing in three priorities:

    • Accelerating the medical companion-app (personalisation, follow-up, stabilization).
    • Increasing and coordinating the multidisciplinary medical community, in shut collaboration with main care physicians.
    • Strengthening prevention and training round weight problems and the accountable use of GLP-1 remedies.





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