Simply this week, Pushmeet Kohli, Google Cloud’s chief scientist, revealed a chunk in a particular AI and science problem of the journal Daedalus, writing: “We’re shifting towards AI that doesn’t simply facilitate science however begins to do science.” With autonomous AI scientists on the horizon, it’s tougher to justify huge efforts to develop super-specialized instruments—even one like AlphaFold, for which DeepMind scientists received a Nobel Prize, or a probably life-saving system like WeatherNext. It additionally heralds a far stranger future for science, during which people and AI methods collaborate as friends—or AI even makes scientific progress by itself.
To be clear, Google doesn’t seem like abandoning its work on specialised AI for science instruments. AlphaGenome and AlphaEarth Foundations, that are educated for genetics and Earth science purposes respectively, have been launched final summer season, and the latest model of WeatherNext got here out in November.
What’s extra, such instruments stay extraordinarily in style amongst scientists. Final yr, as an illustration, Google reported that protein construction predictions from AlphaFold have been utilized by over three million researchers worldwide. And Isomorphic Labs, a Google subsidiary that goals to make use of AlphaFold and associated applied sciences to develop new medicine, simply raised a $2 billion Collection B funding spherical.
However there are concrete indicators of realignment, in each enthusiasm and assets. Final month, the Los Angeles Occasions reported that Google fellow John Jumper, who received the Nobel for AlphaFold, is now engaged on AI coding, not on science-specific AI instruments. It’s not shocking that Google is assigning its finest minds to the coding downside, as the corporate has lately taken a reputational hit as a result of its coding instruments don’t at the moment stand as much as these provided by Anthropic and OpenAI. However it might additionally sign a prioritization of agentic science on Google’s half, as coding skills are key to the success of a few of these methods.
Throughout the business, agentic researcher methods are displaying actual potential. This week, OpenAI announced that considered one of their fashions had disproved an necessary arithmetic conjecture—maybe essentially the most significant contribution that generative AI has made to arithmetic to date, according to some mathematicians.
Importantly, the mannequin utilized by OpenAI shouldn’t be specialised for fixing mathematical issues, and even for analysis; in accordance with the corporate, it’s a general-purpose reasoning mannequin within the vein of GPT-5.5. If normal brokers could make impartial contributions to mathematical analysis, they may quickly have the ability to do the identical in science (although the truth that concepts in science should be verified experimentally makes it a harder area for AI).

